Publications

Research Articles    Reviews & Highlights

Preprints

Nothing to see here just now.

2023

44. Diastereoselective self-assembly of low-symmetry PdnL2n nanocages through coordination-sphere engineering

P. Molinska, A. Tarzia, L. Male, K. E. Jelfs and J. E. M. Lewis*
Angew. Chem. Int. Ed., 2023, 62, e202315451 (open access)

Preprint previously on ChemRxiv


43. Developing sophisticated microenvironments in metal-organic cages

J. E. M. Lewis*
Trends Chem., 2023, 5, 717-719 (open access)



2022

41. Molecular engineering of confined space in metal-organic cages

J. E. M. Lewis*
Chem. Commun., 2022, 58, 13873-13886 (open access)

Invited Feature Article contribution for ChemComm 2022 Emerging Investigators collection


40. Emerging properties from mechanical tethering within a post-synthetically functionalised catenane scaffold

N. Hoyas Pérez, P. S. Sherin, V. Posligua, J. L. Greenfield, M. J. Fuchter, K. E. Jelfs, M. K. Kuimova and J. E. M. Lewis*
Chem. Sci., 2022, 13, 11368-11375 (open access)


39. Pseudo-heterolepticity in Low-Symmetry Metal-Organic Cages

J. E. M. Lewis*
Angew. Chem. Int. Ed., 2022, 61, e202212392 (open access)

Selected as a Hot Paper


2021

38. High-throughput Computational Evaluation of Low Symmetry Pd2L4 Cages to Aid in System Design

A. Tarzia, J. E. M. Lewis* and K. E. Jelfs*
Angew. Chem. Int. Ed., 2021, 60, 20879-20887 (open access)

Quick way to create molecular cages could revamp search for new materials
Preprint previously on ChemRxiv


37. Structural Flexibility in Metal-Organic Cages

A. E. Martín Díaz and J. E. M. Lewis*
Front. Chem., 2021, 9, 706462 (open access)

Invited review contribution for Suprastars of Chemistry collection


36. Rotaxanes as Cages to Control DNA Binding, Cytotoxicity and Cellular Uptake of a Small Molecule

T. Kench, P. A. Summers, M. K. Kuimova, J. E. M. Lewis* and R. Vilar*
Angew. Chem. Int. Ed., 2021, 60, 10928-10934

Selected as a Hot Paper
Highlight: Cancer drugs could be delivered in molecular cages unlocked by light
Preprint previously on ChemRxiv


35. Multi-functional, Low Symmetry Pd2L4 Nanocage Libraries

J. E. M. Lewis*
Chem. Eur. J., 2021, 27, 4454-4460 (open access)

Preprint previously on ChemRxiv


2020

34. Synthetic strategies towards mechanically interlocked oligomers and polymers

N. Hoyas Pérez and J. E. M. Lewis*
Org. Biomol. Chem., 2020, 18, 6757-6780 (open access)

Invited review article


33. Self-assembly of a porous metallo-[5]rotaxane

K. K. G. Wong, N. Hoyas Pérez, A. J. P. White and J. E. M. Lewis*
Chem. Commun., 2020, 56, 10453-10456 (open access)

Highlighted on front cover of issue 72


32. Metallo-Supramolecular Self-Assembly with Reduced-Symmetry Ligands

J. E. M. Lewis* and J. D. Crowley
ChemPlusChem, 2020, 85, 815-827 (open access)

Invited contribution for Supramolecular Chemistry: Young Talents and their Mentors special issue
Featured in Readers’ Choice Special Collection
Among most accessed articles in 2021 in ChemPlusChem


31. Knotting to See Here

J. E. M. Lewis*
Chem, 2020, 6, 14-15

Invited preview of Metal-Peptide Torus Knots from Flexible Short Peptides


30. Conformational Control of Pd2L4 Assemblies with Unsymmetrical Ligands

J. E. M. Lewis,* A. Tarzia, A. J. P. White and K. E. Jelfs
Chem. Sci., 2020, 11, 677-683 (open access)

Included in ‘2019 Chemical Science HOT Article Collection’
Included in ‘Most popular 2019-2020 supramolecular chemistry articles‘ collection


2019

29. Self-templated Synthesis of Amide Catenanes and Formation of a Catenane Coordination Polymer

J. E. M. Lewis*
Org. Biomol. Chem., 2019, 17, 2442-2447

Included in ‘Organic & Biomolecular Chemistry HOT Article Collection’


Postdoctoral and PhD Publications

2021

28. Damming a Molecular Energy Reservoir: Ion-regulated Electronic Energy Shuttling in a [2]Rotaxane
S. Yu, A. Kurpryakov, J. E. M. Lewis, V. Martí-Centelles, S. M. Goldup, J.-L. Pozzo, G. Jonusauskas and N. D. McClenaghan
Chem. Sci., 2021, 12, 9196-9200
Preprint on ChemRxiv

27. Rotaxane CoII Complexes as Field-Induced Single-Ion Magnets
M. Cirulli, E. Salvadori, Z.-H. Zhang, M. Dommett, F. Tuna, H. Bamberger, J. E. M. Lewis, A. Kaur, G. Tizzard, J. van Slageren, R. Crespo-Ortero, S. M. Goldup and M. M. Roessler
Angew. Chem. Int. Ed., 2021, 60, 16051-16058
Preprint on ChemRxiv

2020

26. Rotaxanation as a sequestering template to preclude incidental metal insertion in complex oligochromophores
H. T. Ngo, J. E. M. Lewis, D. T. Payne, F. D’Souza, J. P. Hill, K. Ariga, G. Yoshikawa and S. M. Goldup
Chem. Commun., 2020, 56, 7447-7450

2019

25. An Auxiliary Approach for the Stereoselective Synthesis of Topologically Chiral Catenanes
M. Denis, J. E. M. Lewis, F. Modicom and S. M. Goldup
Chem, 2019, 5, 1512-1520

24. Rotaxane-Based Transition Metal Complexes: Effect of the Mechanical Bond on Structure and Electronic Properties
M. Cirulli, A. Kaur, J. E. M. Lewis, Z. Zhang, J. A. Kitchen, S. M. Goldup and M. M. Roessler
J. Am. Chem. Soc., 2019, 141, 879-889

2018

23. Efficient Multi-Component Active Template Synthesis of Catenanes
J. E. M. Lewis, F. Modicom and S. M. Goldup
J. Am. Chem. Soc., 2018, 140, 4787-4791

2017

22. Porphyrinoid Rotaxanes: Building a Mechanical Picket Fence
T. H. Ngo, J. Labuta, G. N. Lim, W. Webre, F. D’Souza, P. A. Karr, J. E. M. Lewis, J. P. Hill, K. Ariga and S. M. Goldup
Chem. Sci. 2017, 8, 6679-6685

21. Solid state gas adsorption studies with discrete palladium(II) [Pd2(L)4]4+ cages
D. Preston, K.F. White, J. E. M. Lewis, R. A. S. Vasdev, B. F. Abrahams and J. D. Crowley
Chem. Eur. J. 2017, 23, 10559-10567

20. Metal Ions in the Synthesis of Interlocked Molecules
J. E. M. Lewis, P. D. Beer, S. J. Loeb and S. M. Goldup
Chem. Soc. Rev. 2017, 46, 2577-2591

19. Multicavity [PdnL4]2n+ cages with controlled segregated binding of different guests 
D. Preston, J. E. M. Lewis and J. D. Crowley
J. Am. Chem. Soc. 2017, 139, 2379-2386

18. Stepwise, Protecting Group Free Synthesis of [4]Rotaxanes 
J. E. M. Lewis, J. Winn and S. M. Goldup
Molecules 2017, 22, 89:1-12

17. Properties and Emerging Applications of Mechanically Interlocked Ligands 
J. E. M. Lewis, M. Galli, and S. M. Goldup
Chem. Commun. 2017, 53, 298-312

2016

16. Iterative Synthesis Of Oligo[n]rotaxanes in Excellent Yield
J. E. M. Lewis, J. Winn, L. Cera, and S. M. Goldup
J. Am. Chem. Soc.
 2016, 138, 16329-16336

15. Enhanced kinetic stability of [Pd2L4]4+ cages through ligand substitution
D. Preston, S. M. McNeill, J. E. M. Lewis, G. I. Giles and J. D. Crowley
Dalton Trans. 2016, 45, 8050-8060

14. Luminescent Cages: Pendant Emissive Units On [Pd2L4]4+ ”click“ Cages
A. B. S. Elliott, J. E. M. Lewis, G. S. Huff, J. D. Crowley and K. C. Gordon
Inorg. Chem. 2016, 55, 3440-3447

13. High Yielding Synthesis of 2,2′-Bipyridine Macrocycles, Versatile Intermediates In The Synthesis of Rotaxanes
J. E. M. Lewis, R. J. Bordoli, M. Denis, C. J. Fletcher, M. Galli, E. A. Neal, E. M. Rochette and S. M. Goldup
Chem. Sci. 2016, 7, 3154-3161

2015

12. A Stimuli Responsive Rotaxane-Au Catalyst: Regulation of Activity and Diastereoselectivity
M. Galli, J. E. M. Lewis and S. M. Goldup
Angew. Chem. 2015, 54, 13545-13549

11. Biologically Active [Pd2L4]2+ quadruply-stranded helicates: stability and cytotoxicity
S. M. McNeill, D. Preston, J. E. M. Lewis, A. Robert, K. Knerr, J. R. Wright, G. I. Giles and J. D. Crowley
Dalton Trans. 2015, 44, 11129-11136

10. Acid-base driven ligand exchange with Pd(II) “click” complexes
A. Noor, D. L. Maloney, J. E. M. Lewis, W. K. C. Lo and J. D. Crowley
Asian J. Org. Chem. 2015, 4, 208-211

2014

9.  [Re(CO)3]+ complexes of exo-functionalized tridentate “click” macrocycles: Synthesis, stability photophysical properties, bio-conjugation and biological activity
A. Noor, G. S. Huff, S. V. Kumar, J. E. M. Lewis, B. M. Paterson, C. Schieber, H. J. L. Brooks, P. S. Donnelly,
K. C. Gordon, S. C. Moratti and J. D. Crowley
Organometallics 2014, 33, 7031-7043

8. ‘Click’ to Functionalise: Synthesis, Characterisation and Enhancement of the Physical Properties of a Series of Exo– and Endo-Functionalised Pd2L4 Nanocages
J. E. M. Lewis, A. B. S. Elliott, C. J. McAdam, K. C. Gordon and J. D. Crowley
Chem. Sci. 2014, 5, 1833-1843

7. Exo- and Endo-hedral Interactions of Counteranions with Tetracationic Pd2L4 Metallosupramolecular Architectures
J. E. M. Lewis and J. D. Crowley
Supramol. Chem. 2014, 26, 173-181

2013

6. Copper(II) Complexes of a Tripyridyl Ligand: Anion Dependent Metallosupramolecular Structures
J. E. M. Lewis and J. D. Crowley
Aust. J. Chem. 2013, 66, 1447-1454

5. [Fe2L3]4+ Cylinders Derived from Bis(bidentate) 2-Pyridyl-1,2,3-triazole “Click” Ligands: Synthesis, Structures and Exploration of Biological Activity 
S. K. Vellas, J. E. M. Lewis, M. Shankar, A. Sagatova, J. D. A. Tyndall, B. C. Monk, C. M. Fitchett, L. R. Hanton and J. D. Crowley
Molecules, 2013, 18, 6383-6407

4. A Facile ‘Click’ Approach to Functionalised Metallosupramolecular Architectures
J. E. M. Lewis, C. J. McAdam, M. G. Gardiner and J. D. Crowley
Chem. Commun. 2013, 49, 3398-3400

2012

3. fac-Re(CO)3 complexes of 2,6-bis(4-substituted-1,2,3-triazol-1-ylmethyl)pyridine “click” ligands: synthesis, characterisation and photophysical properties
C. B. Anderson, A. B. S. Elliott, J. E. M. Lewis, C. J. McAdam, K. C. Gordon and J. D. Crowley
Dalton Trans. 2012, 41, 14625-14632

2. A multi-component CuAAC ‘click’ approach to an exo functionalised pyridyl-1,2,3-triazole macrocycle: synthesis, characterisation, Cu(I) and Ag(I) complexes
A. Noor, J. E. M. Lewis, S. A. Cameron, S. C. Moratti and J. D. Crowley
Supramol. Chem. 2012, 24, 492-498

1. Stimuli-Responsive Pd2L4 Metallosupramolecular Cages: Towards Targeted Cisplatin Drug Delivery
J. E. M. Lewis, E. L. Gavey, S. A. Cameron and J. D. Crowley
Chem. Sci. 2012, 3, 778-784